Autor: Grzybowski, Andrzej; Barboni, Piero
OCT in Central Nervous System Diseases
The Eye as a Window to the Brain
2nd Edition 2020, 561 p., 159 Illus, 141 in color, Hardcover

About the book:

The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models.
Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”.

Inhalt:

Introduction: Retina Imaging – Past and Present.- OCT Technique – Past, Present and Future.- Optical Coherence Tomography and Optic Nerve Edema.-OCT and Compressive Optic Neuropathy.- Optical Coherence Tomography (OCT) and Multiple Sclerosis (MS).- OCT and Parkinson’s Disease.- Optical Coherence Tomography in Alzheimer’s Disease.- Friedreich’s Ataxia and More: Optical Coherence Tomography Findings in Rare Neurological Syndromes.- Other Neurological Disorders: Migraine, Neurosarcoidosis, Schizophrenia, Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS).- Hereditary Optic Neuropathies.- Trans Neuronal Retrograde Degeneration to OCT in Central Nervous System Diseases.- OCT in Toxic and Nutritional Optic Neuropathies.- Animal Models in Neuro Ophthalmology.- Optical Coherence Tomography (OCT) in Glaucoma.- OCT in Amblyopia.- Conclusion: The Exciting Future of OCT Imaging of Retina.